Major Depressive Disorder (MDD) is a condition that causes depression, a persistent feeling of sadness, and loss of interest in things you normally enjoy.
Depression is a lot more common than you may think; an estimated 21 million adults in the United States have had at least one major depressive episode.1 The JUNIPER MDD Study is evaluating an investigational treatment option for depression associated with Major Depressive Disorder (MDD). This research study hopes to assess the effectiveness of a study drug as an additional or stand-alone possible treatment option for adults with MDD. If you qualify and choose to participate you could have access to a possible treatment option that may help improve your depression symptoms.
You may be eligible to participate if you:
Are between the ages of 18 and 65 years old, inclusive- Experience symptoms of depression, such as:
- low or depressed mood
- decreased interest in pleasurable activities
- feelings of guilt or worthlessness
- lack of energy
- poor concentration
About the JUNIPER MDD Study
The JUNIPER MDD Study will enroll 336 participants with MDD at various study centers located across the Unites States. Participation in the study will consist of 6 visits to the study center, 4 telephone visits, and will last up to 11 weeks (about 2 and a half months), and will include the following periods:
- Screening period: up to 4 weeks to determine if you are eligible
- Study treatment period: 6 weeks
- Follow-up period: 1 week
Participants will receive all study-related care from a dedicated medical team at no cost. Reimbursement for study-related expenses may be available for eligible participants.
Who can take part in the JUNIPER MDD Study?
You may be eligible to participate if you:
- Are between the ages of 18 and 65 years old, inclusive
- Experience symptoms of depression, such as:
- low or depressed mood
- decreased interest in pleasurable activities
- feelings of guilt or worthlessness
- lack of energy
- poor concentration
The JUNIPER MDD Study is assessing the effectiveness of a study drug as an additional or stand-alone possible treatment option for adults with MDD.
Sign Up
What happens if I sign up? We will match you to a study center in your area that needs participants with MDD or notify you when one becomes available. The study team will then contact you and you may have the opportunity to participate if qualified.
If you think you might like to participate in the JUNIPER MDD Study or would like more information, please enter your information below so we can see if you may qualify and can contact you about the studies. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.
Frequently Asked Questions
What is a research study? 
A research study (also called a clinical trial) is a medical study that helps to answer important questions about an investigational drug – these may include how well an investigational study drug works for a certain condition. All medications must be tested in clinical research studies before they can be approved and prescribed to patients.
Why are research studies important?
A research study is the process by which new and innovative medications, interventions and treatments are approved and brought to market, so people can live happier and healthier lives. Even over-the-counter medications, such as NSAIDs, you may have used to counteract a headache, have gone through the clinical research study process before it was available at your local pharmacy.
What is the purpose of the JUNIPER MDD Study?
The JUNIPER MDD Study is assessing the effectiveness of a study drug as an additional or stand-alone possible treatment option for MDD in adults from 18 – 65 years old.
What will the JUNIPER MDD Study involve?
The JUNIPER MDD Study will enroll 336 participants with MDD at various study centers located across the Unites States. Participation in the study will consist of 6 visits to the study center, 4 telephone visits, and will last up to 11 weeks (about 2 and a half months), and will include the following periods:
- Screening period: up to 4 weeks to determine if you are a candidate
- Study treatment period: 6 weeks
- Follow-up period: 1 week
Will I receive compensation?
Participants will receive all study-related care from a dedicated medical team at no cost. Reimbursement for study-related expenses may be available for eligible participants. They may also receive an anti-depressant at no cost after they complete or leave the study. Please discuss this with the study team when they contact you.
Is there a cost to participate?
There is no cost to participate in the JUNIPER MDD Study. If you qualify, you will receive all study-related care from a dedicated medical team at no cost.
What else do I need to consider?
The research team will be able to explain more about what the JUNIPER MDD Study will involve, and it is up to you to decide if you want to take part. Participation in this study is voluntary. Whether or not you decide to participate in this study will not affect your current or future relationships with your doctors. If you decide to participate, you are free to withdraw at any time without affecting those relationships.
How far is the study center?
We match you to a study center within a close travel distance from your home. If we are not running the study in your area currently, with your permission, we will keep you in our database and reach out once a study in your area becomes available. If, at any time, you decided you no longer want your information stored, you can opt out and we will delete your details.
About Major Depressive Disorder (MDD)
Depression is a lot more common than you may think; an estimated 21 million adults in the United States have had at least one major depressive episode.1 MDD is a disease that causes depression, more than just being sad, for most of the day, and lasts for at least two weeks or more.
Primary symptoms of MDD are depressed mood or loss of interest or pleasure; while secondary symptoms of MDD include appetite or weight changes, sleep difficulties, fatigue or loss of energy, and feelings of worthlessness or excessive guilt.2
There are multiple factors believed to cause MDD, including genetic, environmental, and social factors.4 MDD can be managed with various treatment measures, including therapy, medication, and lifestyle modifications.4
